Affymetrix Microbiology Symposia Series

A little bit of self publicity! I will be giving a webinar on Thursday March 29th, 2007 on the work we have done with Affymetrix tiling arrays. This webinar series is sponsored by Affymetrix and highlight creative use of their technology.
We have been working with Affymetrix tiling arrays for about 3 years now, with great succcess. We have designed two tiling arrays for Bacillus anthracis, the causative agent of anthrax. One of the major problem working with such custom-designed arrays is that Affymetrix does not provide any software support for data display and analysis. I'll be describing the array design and a series of algorithm for data analysis, in particular TadPol (Tiling Array Discovery of Polymorphism). TadPol identifies polymorphic regions (SNPs and INDELs) from comparative genome hybridization data. The data is used for genotyping.

If you are interested, here is the web link to register for the webinar. It will be my first webinar, so I'm not sure how it turn out, but it should be an interesting experience!

Here is the announcement:

SNPs, Chips and Transcriptomics in Bacillus anthracis
Thursday, March 29, 2007, 9:00 am (PDT)
Participate in a conference call seminar and Q & A featuring Jacques Ravel, Ph.D. from The Institute for Genomic Research

Dr. Ravel will discuss his research using a custom-designed Affymetrix GeneChip® array that tiles the entire 5.5 Mb genome of Bacillus anthracis Ames Ancestor with 2.1 million overlapping 25-mer oligonucleotides on a single array. Examples of genotyping, polymorphism discovery (SNPs and INDELs), transcript mapping and expression studies will also be discussed. REGISTER FOR SYMPOSIUM

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